FA Cup 2023/24, Second Qualifying Round |
 | 16.09.2023 |  | Mossley AFC | – | AFC Emley | | 1:1 (0:0) |
| Mossley |
FA Cup 2021/22, Preliminary Round |
| 21.08.2021 | | Lower Breck | – | Mossley AFC | | 2:2 (0:0) |
| Liverpool |
FA Cup 2020/21, Second Qualifying Round |
| 03.10.2020 | | Mossley AFC | – | Tadcaster Albion | | 1:1,
pen. 3:4 |
| Mossley |
FA Cup 2019/20, Preliminary Round |
| 24.08.2019 | | Widnes | – | Mossley AFC | | 2:2 (0:2) |
| Widnes |
FA Cup 2018/19, Preliminary Round |
| 04.09.2018 | | Mossley AFC | – | Ossett United | | 1:1 aet
(0:0, 1:1),
pen. 4:2 * |
| Mossley |
FA Cup 2018/19, Preliminary Round |
| 25.08.2018 | | Ossett United | – | Mossley AFC | | 2:2 (0:0) |
| Ossett |
FA Cup 2017/18, First Qualifying Round |
| 02.09.2017 | | Mossley AFC | – | 1874 Northwich | | 2:2 (1:0) |
| Mossley |
FA Cup 2015/16, Preliminary Round |
| 29.08.2015 | | Mossley AFC | – | Bamber Bridge | | 1:1 (1:0) |
| Mossley |
FA Cup 2014/15, Preliminary Round |
| 02.09.2014 | | Mossley AFC | – | Burscough | | 1:1 aet
(1:0, 1:1) * |
| Mossley |
FA Cup 2014/15, Preliminary Round |
| 30.08.2014 | | Burscough | – | Mossley AFC | | 1:1 |
| Burscough |
FA Cup 2013/14, Preliminary Round |
| 31.08.2013 | | Mossley | – | Worksop Parramore | | 1:1 (1:1) |
| Mossley |
FA Cup 2011/12, Preliminary Round |
| 03.09.2011 | | Mossley | – | Runcorn Linnets | | 0:0 |
| |
FA Cup 2010/11, Third Qualifying Round |
| 09.10.2010 | | Lincoln Moorlands Railway | – | Mossley | | 1:1 |
| |
FA Cup 2007/08, Preliminary Round |
| 02.09.2007 | | Woodley Sports | – | Mossley | | 1:1 |
| |
FA Cup 2005/06, Preliminary Round |
| 27.08.2005 | | Sheffield | – | Mossley | | 2:2 |
| |
FA Cup 2003/04, Preliminary Round |
| | | Mossley | – | Curzon Ashton | | 1:1 |
| |
FA Cup 2000/01, Third Qualifying Round |
| | | Mossley | – | Frickley Athletic | | 1:1 |
| |
FA Cup 1998/99, Second Qualifying Round |
| | | Billingham Synthonia | – | Mossley | | 0:0 |
| |
FA Cup 1995/96, Preliminary Round |
| | | Maltby Miners Welfare | – | Mossley | | 3:3 |
| |
FA Cup 1994/95, Preliminary Round |
| | | Ossett Town | – | Mossley | | 0:0 |
| |
FA Cup 1992/93, First Qualifying Round |
| | | Mossley | – | Borrowash Victoria | | 0:0 |
| |
FA Cup 1991/92, Second Qualifying Round |
| | | Mossley | – | Winsford United | | 1:1 |
| |
FA Cup 1991/92, First Qualifying Round |
| | | Flixton | – | Mossley | | 1:1 |
| |
FA Cup 1989/90, Fourth Qualifying Round |
| | | Mossley | – | Bishop Auckland | | 1:1 |
| |
FA Cup 1989/90, Third Qualifying Round |
| | | Curzon Ashton | – | Mossley | | 1:1 |
| |
FA Cup 1989/90, First Qualifying Round |
| | | Mossley | – | South Liverpool | | 0:0 |
| |
FA Cup 1986/87, First Qualifying Round |
| | | Eastwood Town | – | Mossley | | 1:1 aet * |
| |
FA Cup 1986/87, First Qualifying Round |
| | | Mossley | – | Eastwood Town | | 3:3 |
| |
FA Cup 1983/84, Fourth Qualifying Round |
| | | Workington | – | Mossley | | 0:0 |
| |
FA Cup 1979/80, Second Qualifying Round |
| | | Macclesfield Town | – | Mossley | | 0:0 |
| |
FA Cup 1977/78, Third Qualifying Round |
| | | Mossley | – | Winsford United | | 3:3 aet * |
| |
FA Cup 1977/78, Third Qualifying Round |
| | | Winsford United | – | Mossley | | 1:1 |
| |
FA Cup 1973/74, Second Qualifying Round |
| | | Mossley | – | Prestwich Heys | | 1:1 |
| |
FA Cup 1972/73, First Qualifying Round |
| | | Mossley | – | Stalybridge Celtic | | 1:1 |
| |
FA Cup 1971/72, Second Qualifying Round |
| | | Mossley | – | Hyde United | | 0:0 |
| |
FA Cup 1971/72, First Qualifying Round |
| | | Mossley | – | Prestwich Heys | | 2:2 |
| |
FA Cup 1969/70, First Round Proper |
| 15.11.1969 | | Stockport County | – | Mossley | | 1:1 (0:0) |
| |
FA Cup 1969/70, Second Qualifying Round |
| | | Mossley | – | Rossendale United | | 0:0 |
| |
FA Cup 1968/69, First Qualifying Round |
| | | Hyde United | – | Mossley | | 2:2 |
| |
FA Cup 1966/67, Second Qualifying Round |
| | | Mossley | – | Northwich Victoria | | 1:1 |
| |
FA Cup 1962/63, Second Qualifying Round |
| | | Droylsden | – | Mossley | | 0:0 |
| |
FA Cup 1960/61, Preliminary Round |
| | | Rossendale United | – | Mossley | | 1:1 |
| |
FA Cup 1959/60, Preliminary Round |
| | | Skelmersdale United | – | Mossley | | 0:0 |
| |
FA Cup 1957/58, First Qualifying Round |
| | | Bacup Borough | – | Mossley | | 1:1 |
| |
FA Cup 1957/58, Preliminary Round |
| | | Horwich Railway Mechanics Institute | – | Mossley | | 1:1 |
| |
FA Cup 1956/57, Second Qualifying Round |
| | | Darwen | – | Mossley | | 1:1 |
| |
FA Cup 1955/56, Preliminary Round |
| | | Mossley | – | Lytham | | 1:1 |
| |
FA Cup 1953/54, Fourth Qualifying Round |
| | | Mossley | – | Rhyl |  | 1:1 |
| |
FA Cup 1949/50, Second Round Proper |
| 10.12.1949 | | Nuneaton Borough | – | Mossley | | 0:0 |
| |
