Europa League 2022/23, Group E |
 | 03.11.2022 |  | Sheriff | – | Omonia |  | 1:0 (0:0) |
| Chişinău |
Europa League 2022/23, Group E |
| 27.10.2022 | | Omonia | – | Real Sociedad |  | 0:2 (0:1) |
| Nicosia |
Europa League 2022/23, Group E |
| 13.10.2022 |  | Manchester United | – | Omonia | | 1:0 (0:0) |
| Manchester |
Europa League 2022/23, Group E |
| 06.10.2022 | | Omonia | – | Manchester United | | 2:3 (1:0) |
| Nicosia |
Europa League 2022/23, Group E |
| 15.09.2022 | | Real Sociedad | – | Omonia | | 2:1 (1:0) |
| San Sebastián |
Europa League 2022/23, Group E |
| 08.09.2022 | | Omonia | – | Sheriff | | 0:3 (0:1) |
| Nicosia |
Europa League 2021/22, Play-off Round |
| 26.08.2021 |  | Antwerp | – | Omonia | | 2:0 aet
(1:0, 2:0),
pen. 3:2 |
| Antwerpen |
Europa League 2021/22, Third qualifying round |
| 10.08.2021 |  | Flora | – | Omonia | | 2:1 aet
(0:1, 2:1),
pen. 4:5 |
| Tallinn |
Europa League 2020/21, Group E |
| 10.12.2020 |  | PSV | – | Omonia | | 4:0 (1:0) |
| Eindhoven |
Europa League 2020/21, Group E |
| 26.11.2020 | | Granada | – | Omonia | | 2:1 (1:0) * |
| Granada |
Europa League 2020/21, Group E |
| 05.11.2020 | | Omonia | – | Granada | | 0:2 (0:1) |
| Nicosia |
Europa League 2020/21, Group E |
| 29.10.2020 | | Omonia | – | PSV | | 1:2 (1:1) |
| Nicosia |
Europa League 2016/17, Second qualifying round |
| 14.07.2016 |  | Beitar | – | Omonia | | 1:0 (0:0) |
| Jerusalem |
Europa League 2015/16, First Qualifying Round |
| 02.07.2015 |  | Dinamo Batumi | – | Omonia | | 1:0 (1:0) |
| Zestaponi |
Europa League 2014/15, Play-off Round |
| 28.08.2014 | | Omonia | – | Dynamo Moscow |  | 1:2 (1:1) |
| Nicosia |
Europa League 2013/14, Second qualifying round |
| 25.07.2013 | | Omonia | – | Astra |  | 1:2 (0:1) |
| Nicosia |
Europa League 2011/12, Play-off Round |
| 25.08.2011 |  | Red Bull | – | Omonia | | 1:0 (0:0) |
| Salzburg |
Europa League 2011/12, Third qualifying round |
| 04.08.2011 | | Den Haag | – | Omonia | | 1:0 (0:0) |
| Den Haag |
Europa League 2010/11, Play-off Round |
| 19.08.2010 | | Omonia | – | Metalist |  | 0:1 (0:1) |
| Nicosia |
Europa League 2009/10, Third qualifying round |
| 30.07.2009 | | Vaslui | – | Omonia | | 2:0 (1:0) |
| Vaslui |
UEFA Cup 2008/09, First Round |
| 02.10.2008 | | Manchester City | – | Omonia | | 2:1 (0:0) |
| Manchester |
UEFA Cup 2008/09, First Round |
| 18.09.2008 | | Omonia | – | Manchester City | | 1:2 (0:0) |
| Nicosia |
UEFA Cup 2007/08, Second qualifying round |
| 30.08.2007 |  | CSKA Sofia | – | Omonia | | 2:1 (1:1) |
 | Sofia |
UEFA Cup 2006/07, Second qualifying round |
| 24.08.2006 | | Liteks | – | Omonia | | 2:1 (2:1) |
| Lovech |
UEFA Cup 2005/06, Second Qualifying Round |
| 11.08.2005 | | Dinamo Bucureşti | – | Omonia | | 3:1 (3:1) |
| Bucureşti |
UEFA Cup 2004/05, Second Qualifying Round |
| 26.08.2004 | | CSKA Sofia | – | Omonia | | 3:1 aet
(0:0, 1:1) |
| Sofia |
UEFA Cup 2000/01, Qualifying round |
| 24.08.2000 | | Neftochimik | – | Omonia | | 2:1 (2:1) |
| Burgas |
UEFA Cup 1999/00, 1/64 finals |
| 30.09.1999 |  | Juventus | – | Omonia | | 5:0 (1:0) |
| Palermo |
UEFA Cup 1999/00, 1/64 finals |
| 16.09.1999 | | Omonia | – | Juventus | | 2:5 (0:4) |
| Nicosia |
UEFA Cup 1998/99, Second Qualifying Round |
| 25.08.1998 | | Rapid Wien | – | Omonia | | 2:0 (1:0) |
| Wien |
UEFA Cup 1998/99, First Qualifying Round |
| 29.07.1998 |  | Linfield | – | Omonia | | 5:3 (3:3) |
| Belfast |
UEFA Cup 1995/96, 1/32 finals |
| 26.09.1995 | | Omonia | – | Lazio | | 1:2 (0:1) |
| Nicosia |
UEFA Cup 1995/96, 1/32 finals |
| 12.09.1995 | | Lazio | – | Omonia | | 5:0 (2:0) |
| Roma |
UEFA Cup 1990/91, 1/16 finals |
| 07.11.1990 | | Anderlecht | – | Omonia | | 3:0 (2:0) |
| Bruxelles |
UEFA Cup 1990/91, 1/32 finals |
| 19.09.1990 | | Slavia Sofia | – | Omonia | | 2:1 (1:0) |
| Sofia |
UEFA Cup 1986/87, 1/32 finals |
| 17.09.1986 | | Sportul | – | Omonia | | 1:0 (0:0) |
| Bucureşti |
