Copa Sudamericana 2019, Final |
 | 09.11.2019 |  | Independiente del Valle | – | Colón |  | 3:1 (2:0) |
| Paraguay, Asunción |
Copa Sudamericana 2019, Semifinal |
| 26.09.2019 |  | Atlético Mineiro | – | Colón | | 2:1 (1:0),
pen. 3:4 |
| Belo Horizonte |
Copa Sudamericana 2019, Semifinal |
| 19.09.2019 | | Colón | – | Atlético Mineiro | | 2:1 (0:1) |
| Santa Fe |
Copa Sudamericana 2019, Quarterfinal |
| 15.08.2019 | | Colón | – | Zulia |  | 4:0 (0:0) |
| Santa Fe |
Copa Sudamericana 2019, Quarterfinal |
| 08.08.2019 | | Zulia | – | Colón | | 1:0 (0:0) |
| Maracaibo |
Copa Sudamericana 2019, Round of 16 |
| 18.07.2019 | | Argentinos Juniors | – | Colón | | 0:1 (0:0),
pen. 3:4 |
| Buenos Aires |
Copa Sudamericana 2019, Round of 16 |
| 11.07.2019 | | Colón | – | Argentinos Juniors | | 0:1 (0:1) |
| Santa Fe |
Copa Sudamericana 2019, Second round |
| 28.05.2019 | | Colón | – | River Plate |  | 3:1 (2:1) |
| Santa Fe |
Copa Sudamericana 2019, Second round |
| 21.05.2019 | | River Plate | – | Colón | | 0:0 |
| Montevideo |
Copa Sudamericana 2019, First stage |
| 16.04.2019 | | Colón | – | Deportivo Municipal |  | 2:0 (1:0) |
| Santa Fe |
Copa Sudamericana 2019, First stage |
| 19.03.2019 | | Deportivo Municipal | – | Colón | | 0:3 (0:1) |
| Lima |
Copa Sudamericana 2018, Round of 16 |
| 04.10.2018 | | Colón | – | Junior |  | 1:1 (0:0) |
| Santa Fe |
Copa Sudamericana 2018, Round of 16 |
| 26.09.2018 | | Junior | – | Colón | | 1:0 (0:0) |
| Barranquilla |
Copa Sudamericana 2018, Second round |
| 16.08.2018 | | Colón | – | São Paulo | | 0:1 (0:0),
pen. 5:3 |
| Santa Fe |
Copa Sudamericana 2018, Second round |
| 02.08.2018 | | São Paulo | – | Colón | | 0:1 (0:0) |
| São Paulo |
Copa Sudamericana 2018, First stage |
| 06.03.2018 | | Colón | – | Zamora | | 1:0 (0:0) |
| Santa Fe |
Copa Sudamericana 2018, First stage |
| 13.02.2018 | | Zamora | – | Colón | | 0:2 (0:1) |
| Barinas |
Copa Sudamericana 2012, Round of 16 |
| 23.10.2012 |  | Cerro Porteño | – | Colón | | 2:1 (1:1) |
| Asunción |
Copa Sudamericana 2012, Round of 16 |
| 27.09.2012 | | Colón | – | Cerro Porteño | | 1:2 (1:1) |
| Santa Fe |
Copa Sudamericana 2012, Second round |
| 30.08.2012 | | Racing Club | – | Colón | | 1:2 (1:0) |
| Avellaneda |
Copa Sudamericana 2012, Second round |
| 23.08.2012 | | Colón | – | Racing Club | | 3:1 (0:0) |
| Santa Fe |
Copa Sudamericana 2003, Section 1, Second Stage |
| 09.10.2003 | | Boca Juniors | – | Colón | | 2:1 (0:0) |
| Salta |
Copa Sudamericana 2003, Section 1, Second Stage |
| 24.09.2003 | | Colón | – | Boca Juniors | | 1:1 (0:1) |
| Santa Fe |
Copa Sudamericana 2003, Section 1, First Stage |
| 28.08.2003 | | Vélez Sársfield | – | Colón | | 1:4 (0:1) |
| Buenos Aires |
Copa Sudamericana 2003, Section 1, First Stage |
| 12.08.2003 | | Colón | – | Vélez Sársfield | | 3:1 (1:0) |
| Santa Fe |
