Copa Libertadores 2022, Second round |
 | 02.03.2022 |  | Guaraní | – | América |  | 2:3 (2:0),
pen. 4:5 |
| Asunción |
Copa Libertadores 2021, Second round |
| 18.03.2021 |  | Atlético Nacional | – | Guaraní | | 3:0 (2:0) |
| Medellín |
Copa Libertadores 2021, Second round |
| 11.03.2021 | | Guaraní | – | Atlético Nacional | | 0:2 (0:1) |
| Asunción |
Copa Libertadores 2020, Round of 16 |
| 03.12.2020 | | Grêmio | – | Guaraní | | 2:0 (1:0) * |
| Porto Alegre |
Copa Libertadores 2020, Round of 16 |
| 26.11.2020 | | Guaraní | – | Grêmio | | 0:2 (0:0) * |
| Asunción |
Copa Libertadores 2020, Group B |
| 10.03.2020 | | Palmeiras | – | Guaraní | | 3:1 (0:0) |
| São Paulo |
Copa Libertadores 2020, Second qualifying stage |
| 12.02.2020 | | Corinthians | – | Guaraní | | 2:1 (2:0) |
| São Paulo |
Copa Libertadores 2018, Third qualifying stage |
| 15.02.2018 | | Junior | – | Guaraní | | 1:0 (0:0) |
| Barranquilla |
Copa Libertadores 2018, Second qualifying stage |
| 30.01.2018 |  | Carabobo | – | Guaraní | | 1:0 (1:0) |
| Mérida |
Copa Libertadores 2017, Round of 16 |
| 04.07.2017 | | Guaraní | – | River Plate |  | 0:2 (0:1) |
| Asunción |
Copa Libertadores 2017, Group 8 |
| 27.04.2017 | | Grêmio | – | Guaraní | | 4:1 (3:1) |
| Porto Alegre |
Copa Libertadores 2016, Preliminary Round |
| 04.02.2016 |  | Independiente del Valle | – | Guaraní | | 1:0 (1:0) |
| Sangolquí |
Copa Libertadores 2015, Semifinal |
| 14.07.2015 | | River Plate | – | Guaraní | | 2:0 (0:0) |
| Buenos Aires |
Copa Libertadores 2015, Group 8 |
| 24.02.2015 | | Racing Club | – | Guaraní | | 4:1 (1:0) |
| Avellaneda |
Copa Libertadores 2014, Preliminary Round |
| 06.02.2014 | | Guaraní | – | Universidad de Chile |  | 2:3 (1:0) |
| Asunción |
Copa Libertadores 2014, Preliminary Round |
| 30.01.2014 | | Universidad de Chile | – | Guaraní | | 1:0 (0:0) |
| Santiago |
Copa Libertadores 2011, Group 7 |
| 13.04.2011 | | Guaraní | – | Deportes Tolima | | 0:2 (0:0) |
| Asunción |
Copa Libertadores 2011, Group 7 |
| 30.03.2011 | | Guaraní | – | Cruzeiro | | 0:2 (0:1) |
| Asunción |
Copa Libertadores 2011, Group 7 |
| 17.03.2011 | | Estudiantes | – | Guaraní | | 5:1 (3:0) |
| La Plata |
Copa Libertadores 2011, Group 7 |
| 09.03.2011 | | Guaraní | – | Estudiantes | | 1:2 (1:0) |
| Asunción |
Copa Libertadores 2011, Group 7 |
| 22.02.2011 | | Cruzeiro | – | Guaraní | | 4:0 (1:0) |
| Belo Horizonte |
Copa Libertadores 2011, Group 7 |
| 15.02.2011 | | Deportes Tolima | – | Guaraní | | 1:0 (0:0) |
| Ibagué |
Copa Libertadores 2009, Group 2 |
| 16.04.2009 | | Deportivo Táchira | – | Guaraní Asunción | | 2:1 (0:1) |
| San Cristóbal |
Copa Libertadores 2009, Group 2 |
| 08.04.2009 | | Boca Juniors | – | Guaraní Asunción | | 3:1 (2:1) * |
| Buenos Aires |
Copa Libertadores 2009, Group 2 |
| 18.03.2009 | | Guaraní Asunción | – | Boca Juniors | | 1:3 (1:0) |
| Asunción |
Copa Libertadores 2009, Group 2 |
| 24.02.2009 | | Deportivo Cuenca | – | Guaraní Asunción | | 4:0 (1:0) |
| Cuenca |
Copa Libertadores 2009, Group 2 |
| 10.02.2009 | | Guaraní Asunción | – | Deportivo Táchira | | 1:2 (1:1) |
| Asunción |
Copa Libertadores 2004, Group 7 |
| 14.04.2004 | | Barcelona | – | Guaraní Asunción | | 2:0 (1:0) |
| Guayaquil |
Copa Libertadores 2004, Group 7 |
| 25.03.2004 | | Guaraní Asunción | – | Santos | | 1:2 (0:0) |
| Asunción |
Copa Libertadores 1997, 1/8 finals |
| 06.05.1997 | | Grêmio | – | Guaraní Asunción | | 2:1 (0:0),
pen. 2:1 |
| Porto Alegre |
Copa Libertadores 1997, Group 1 |
| 28.02.1997 |  | Bolívar | – | Guaraní Asunción | | 4:1 (2:0) |
| La Paz |
Copa Libertadores 1997, Group 1 |
| 25.02.1997 | | Oriente Petrolero | – | Guaraní Asunción | | 4:1 (0:1) |
| Cochabamba |
Copa Libertadores 1985, First Round, Group 3 |
| 03.04.1985 | | América de Cali | – | Guaraní Asunción | | 2:1 (1:0) |
| Santiago de Cali |
Copa Libertadores 1985, First Round, Group 3 |
| 31.03.1985 | | Los Millonarios | – | Guaraní Asunción | | 5:1 (3:0) |
| Bogotá |
Copa Libertadores 1985, First Round, Group 3 |
| 27.03.1985 | | Cerro Porteño | – | Guaraní Asunción | | 3:1 (1:0) |
| Asunción |
Copa Libertadores 1971, First Round, Group 4 |
| 17.03.1971 | | Colo-Colo | – | Guaraní Asunción | | 3:2 (1:2) |
| Santiago |
Copa Libertadores 1971, First Round, Group 4 |
| 13.03.1971 | | Unión Española | – | Guaraní Asunción | | 2:1 (0:0) |
| Santiago |
Copa Libertadores 1970, Second round, group 2 |
| 26.04.1970 |  | Peñarol | – | Guaraní Asunción | | 1:0 (0:0) |
| Montevideo |
Copa Libertadores 1970, Second round, group 2 |
| 22.04.1970 | | LDU | – | Guaraní Asunción | | 1:0 (0:0) |
| Quito |
Copa Libertadores 1968, Second round, group 3 |
| 04.04.1968 | | Palmeiras | – | Guaraní Asunción | | 2:1 (1:1) |
| São Paulo |
Copa Libertadores 1968, Second round, group 3 |
| 13.03.1968 | | Universidad Católica | – | Guaraní Asunción | | 4:1 (2:1) |
| Santiago |
Copa Libertadores 1968, First Round, Group 4 |
| 12.02.1968 | | Peñarol | – | Guaraní Asunción | | 2:0 (1:0) |
| Montevideo |
Copa Libertadores 1967, First Round, Group 3 |
| 15.05.1967 | | Guaraní Asunción | – | Cerro Porteño | | 1:2 (0:1) |
| Asunción |
Copa Libertadores 1967, First Round, Group 3 |
| 30.04.1967 | | Guaraní Asunción | – | Nacional Montevideo | | 0:1 (0:0) |
| Uruguay, Montevideo |
Copa Libertadores 1967, First Round, Group 3 |
| 23.04.1967 | | Nacional Montevideo | – | Guaraní Asunción | | 3:1 (1:1) |
| Montevideo |
Copa Libertadores 1967, First Round, Group 3 |
| 18.03.1967 | | Colo-Colo | – | Guaraní Asunción | | 1:0 (0:0) |
| Santiago |
Copa Libertadores 1967, First Round, Group 3 |
| 05.03.1967 | | Barcelona | – | Guaraní Asunción | | 2:1 (2:1) |
| Guayaquil |
Copa Libertadores 1967, First Round, Group 3 |
| 26.02.1967 | | Cerro Porteño | – | Guaraní Asunción | | 1:0 (0:0) |
| Asunción |
Copa Libertadores 1966, Semifinal group 1 |
| 26.04.1966 | | Independiente Avellaneda | – | Guaraní Asunción | | 2:1 (1:1) |
| Avellaneda |
Copa Libertadores 1966, Semifinal group 1 |
| 21.04.1966 | | River Plate | – | Guaraní Asunción | | 3:1 (1:0) |
| Buenos Aires |
Copa Libertadores 1966, Semifinal group 1 |
| 14.04.1966 | | Guaraní Asunción | – | Independiente Avellaneda | | 0:2 (0:0) |
| Asunción |
Copa Libertadores 1966, Semifinal group 1 |
| 06.04.1966 | | Guaraní Asunción | – | River Plate | | 1:3 (0:2) |
| Asunción |
Copa Libertadores 1966, Semifinal group 1 |
| 30.03.1966 | | Guaraní Asunción | – | Boca Juniors | | 1:3 (0:1) |
| Asunción |
Copa Libertadores 1966, First Round, Group 2 |
| 08.03.1966 | | Universidad de Chile | – | Guaraní Asunción | | 2:0 (1:0) |
| Santiago |
Copa Libertadores 1966, First Round, Group 2 |
| 05.03.1966 | | Universidad Católica | – | Guaraní Asunción | | 2:0 (1:0) |
| Santiago |
Copa Libertadores 1965, Group 3 |
| 10.03.1965 | | Peñarol | – | Guaraní Asunción | | 2:0 (1:0) |
| Montevideo |
Superclásico
Copa Newton
Copa Lipton
Copa Rosa
Copa Félix Bogado
Copa Carlos Dittborn
Copa Ramón Castilla
Copa Rio Branco
Copa Rodrigues Alves
Taça Bernardo O'Higgins
Copa Artigas
Copa Paz del Chaco
Copa del Pacífico
