CAF Champions League 2022/23, Group D |
 | 17.02.2023 |  | Al-Merrikh | – | Zamalek SC |  | 0:0 |
| Libya, Benghazi |
CAF Champions League 2021/22, Group D |
| 01.04.2022 | | Zamalek SC | – | Sagrada Esperança |  | 0:0 |
| Cairo |
CAF Champions League 2021/22, Group D |
| 19.03.2022 | | Atlético Petróleos | – | Zamalek SC | | 0:0 |
| Luanda |
CAF Champions League 2021/22, Group D |
| 19.02.2022 | | Sagrada Esperança | – | Zamalek SC | | 0:0 |
| Luanda |
CAF Champions League 2021/22, Group D |
| 12.02.2022 | | Zamalek SC | – | Atlético Petróleos | | 2:2 (1:2) |
| Cairo |
CAF Champions League 2020/21, Group D |
| 23.02.2021 |  | Teungueth | – | Zamalek SC | | 0:0 |
| Thiès |
CAF Champions League 2020/21, Group D |
| 12.02.2021 | | Zamalek SC | – | MC Alger |  | 0:0 |
| Cairo |
CAF Champions League 2019/20, Group A |
| 01.02.2020 | | Primeiro de Agosto | – | Zamalek SC | | 0:0 |
| Luanda |
CAF Champions League 2019/20, Group A |
| 24.01.2020 | | Zamalek SC | – | TP Mazembe |  | 0:0 |
| Cairo |
CAF Champions League 2019/20, Group A |
| 28.12.2019 |  | ZESCO United | – | Zamalek SC | | 1:1 (0:0) |
| Ndola |
CAF Champions League 2017, Group B |
| 09.07.2017 | | Zamalek SC | – | Al Ahly Tripoli |  | 2:2 (1:1) |
| Cairo |
CAF Champions League 2017, Group B |
| 02.06.2017 | | Zamalek SC | – | USM Alger | | 1:1 (0:1) |
| Alexandria |
CAF Champions League 2017, Group B |
| 23.05.2017 | | Al Ahly Tripoli | – | Zamalek SC | | 0:0 |
| Tunisia, Sfax |
CAF Champions League 2016, Second round |
| 19.04.2016 | | MO Béjaïa | – | Zamalek | | 1:1 (0:0) |
| Béjaïa |
CAF Champions League 2014, Group A |
| 27.07.2014 | | Zamalek | – | TP Mazembe | | 0:0 |
| Alexandria |
CAF Champions League 2014, 1/8 finals |
| 22.03.2014 | | Nkana | – | Zamalek | | 0:0 |
| Kitwe |
CAF Champions League 2014, Round of 32 |
| 07.03.2014 | | Kabuscorp | – | Zamalek | | 0:0 |
| Luanda |
CAF Champions League 2013, Group A |
| 24.07.2013 | | Zamalek | – | Al Ahly Cairo | | 1:1 (1:0) |
| El Gouna |
CAF Champions League 2013, 1/8 finals |
| 05.05.2013 |  | Saint George | – | Zamalek | | 2:2 (2:1) |
| Addis Ababa |
CAF Champions League 2013, 1/8 finals |
| 20.04.2013 | | Zamalek | – | Saint George | | 1:1 (0:0) |
| Cairo |
CAF Champions League 2013, Round of 32 |
| 06.04.2013 | | Vita | – | Zamalek | | 0:0 |
| Kinshasa |
CAF Champions League 2013, Preliminary Round |
| 02.03.2013 |  | Gazelle | – | Zamalek | | 0:0 |
| N'Djamena |
CAF Champions League 2012, Group B |
| 16.09.2012 | | Al Ahly Cairo | – | Zamalek | | 1:1 (0:1) |
| Alexandria |
CAF Champions League 2012, Group B |
| 01.09.2012 | | Zamalek | – | Berekum Chelsea |  | 1:1 (1:1) |
| Cairo |
CAF Champions League 2012, Preliminary Round |
| 18.02.2012 |  | Young Africans | – | Zamalek | | 1:1 (1:0) |
| Dar es Salaam |
CAF Champions League 2008, Group A |
| 14.09.2008 | | Zamalek | – | Al Ahly Cairo | | 2:2 (1:1) |
| Cairo |
CAF Champions League 2008, Group A |
| 16.08.2008 | | Zamalek | – | ASEC |  | 0:0 |
| Cairo |
CAF Champions League 2007, 1/16 Finals |
| 17.03.2007 | | Zamalek | – | Al Hilal | | 2:2 (1:0) |
| |
CAF Champions League 2005, Group B |
| 24.07.2005 | | Zamalek | – | Espérance |  | 1:1 (1:1) |
| |
CAF Champions League 2005, Group B |
| 10.07.2005 | | Zamalek | – | Etoile du Sahel | | 1:1 (0:0) |
| |
CAF Champions League 2005, Group B |
| 26.06.2005 | | ASEC | – | Zamalek | | 1:1 (0:1) |
| |
CAF Champions League 2005, 1/8 Finals |
| 09.04.2005 | | Aviação | – | Zamalek | | 1:1 (1:1) |
| |
CAF Champions League 2002, Final |
| 30.11.2002 |  | Raja | – | Zamalek | | 0:0 |
| Casablanca |
CAF Champions League 2002, Semifinal |
| 03.11.2002 | | TP Mazembe | – | Zamalek | | 1:1 (1:0) |
| |
CAF Champions League 2002, Group B |
| 17.08.2002 | | Espérance | – | Zamalek | | 1:1 |
| Tunis |
CAF Champions League 2002, Second Round |
| 27.04.2002 | | Nkana | – | Zamalek | | 1:1 |
| |
CAF Champions League 2002, First Round |
| 24.03.2002 |  | APR FC | – | Zamalek | | 0:0 |
| |
African Cup of Champions Clubs 1994, Final |
| 04.12.1994 | | Zamalek | – | Espérance | | 0:0 |
| Cairo |
African Cup of Champions Clubs 1993, Final |
| 10.12.1993 | | Zamalek | – | Asante Kotoko | | 0:0 aet,
pen. 7:6 |
| Cairo |
African Cup of Champions Clubs 1993, Final |
| 26.11.1993 | | Asante Kotoko | – | Zamalek | | 0:0 |
| Kumasi |
African Cup of Champions Clubs 1997, First Round |
| | | Saint George | – | Zamalek | | 1:1 |
| |
African Cup of Champions Clubs 1996, Quarterfinal |
| | | COD Meknès | – | Zamalek | | 2:2 |
| |
African Cup of Champions Clubs 1994, Second Round |
| |  | Gor Mahia | – | Zamalek | | 1:1 |
| |
African Cup of Champions Clubs 1994, Quarterfinal |
| |  | Sogara | – | Zamalek | | 2:2 |
| |
African Cup of Champions Clubs 1993, Quarterfinal |
| | | MC Oran | – | Zamalek | | 1:1 |
| |
African Cup of Champions Clubs 1986, First Round |
| | | Panthères Noires | – | Zamalek | | 1:1 |
| |
African Cup of Champions Clubs 1985, Second Round |
| | | Al Hilal | – | Zamalek | | 1:1 |
| |
African Cup of Champions Clubs 1984, First Round |
| | | Sfaxien | – | Zamalek | | 1:1 |
| |
African Cup of Champions Clubs 1984, Quarterfinal |
| | | Nkana Red Devils | – | Zamalek | | 1:1 |
| |
