Copa Libertadores 2023, Group B |
 | 08.06.2023 | | Metropolitanos | – | Independiente | | 0:1 (0:0) |
| Caracas |
Copa Libertadores 2023, Group B |
| 23.05.2023 | | Independiente | – | Nacional | | 2:1 (1:1) |
| Medellín |
Copa Libertadores 2023, Group B |
| 03.05.2023 | | Independiente | – | Metropolitanos | | 4:2 (4:1) |
| Medellín |
Copa Libertadores 2023, Third round |
| 15.03.2023 | | Independiente | – | Magallanes | | 2:0 (2:0) |
| Medellín |
Copa Libertadores 2023, Second round |
| 01.03.2023 | | Independiente | – | El Nacional | | 2:1 (0:0) |
| Medellín |
Copa Libertadores 2020, Group H |
| 22.10.2020 | | Libertad | – | Independiente | | 2:4 (1:1) |
| Asunción |
Copa Libertadores 2020, Group H |
| 30.09.2020 | | Caracas | – | Independiente | | 0:2 (0:0) |
| Caracas |
Copa Libertadores 2020, Third qualifying stage |
| 18.02.2020 | | Independiente | – | Atlético Tucumán | | 1:0 (1:0) |
| Medellín |
Copa Libertadores 2020, Second qualifying stage |
| 04.02.2020 | | Independiente | – | Deportivo Táchira | | 4:0 (3:0) |
| Medellín |
Copa Libertadores 2017, Group 3 |
| 25.05.2017 | | River Plate | – | Independiente | | 1:2 (0:0) |
| Buenos Aires |
Copa Libertadores 2017, Group 3 |
| 26.04.2017 | | Melgar | – | Independiente | | 1:2 (0:0) |
| Arequipa |
Copa Libertadores 2017, Group 3 |
| 20.04.2017 | | Independiente | – | Melgar | | 2:0 (1:0) |
| Medellín |
Copa Libertadores 2010, Group 1 |
| 08.04.2010 | | Independiente Medellín | – | Cerro Porteño | | 1:0 (0:0) |
| Medellín |
Copa Libertadores 2009, Group 4 |
| 15.04.2009 | | Independiente Medellín | – | São Paulo | | 2:1 (2:1) |
| Medellín |
Copa Libertadores 2009, Preliminary Round |
| 28.01.2009 | | Independiente Medellín | – | Peñarol | | 4:0 (3:0) |
| Medellín |
Copa Libertadores 2005, Group 1 |
| 10.05.2005 | | Atlético-PR | – | Independiente Medellín | | 0:4 (0:0) |
| Curitiba |
Copa Libertadores 2005, Group 1 |
| 26.04.2005 | | Independiente Medellín | – | América de Cali | | 2:0 (1:0) |
| Medellín |
Copa Libertadores 2005, Group 1 |
| 17.03.2005 | | Independiente Medellín | – | Libertad | | 4:2 (3:2) |
| Medellín |
Copa Libertadores 2003, Quarterfinal |
| 29.05.2003 | | Independiente Medellín | – | Grêmio | | 2:1 (1:1) |
| Medellín |
Copa Libertadores 2003, 1/8 finals |
| 23.04.2003 | | Cerro Porteño | – | Independiente Medellín | | 0:1 (0:1) |
| Asunción |
Copa Libertadores 2003, Group 7 |
| 10.04.2003 | | Independiente Medellín | – | Colo-Colo | | 2:0 (1:0) |
| Medellín |
Copa Libertadores 2003, Group 7 |
| 03.04.2003 | | Barcelona | – | Independiente Medellín | | 2:4 (1:2) |
| Guayaquil |
Copa Libertadores 2003, Group 7 |
| 26.03.2003 | | Independiente Medellín | – | Boca Juniors | | 1:0 (0:0) |
| Medellín |
Copa Libertadores 2003, Group 7 |
| 27.02.2003 | | Independiente Medellín | – | Barcelona | | 1:0 (1:0) |
| Medellín |
Copa Libertadores 1994, 1/8 finals |
| 27.04.1994 | | Independiente Medellín | – | Universitario de Deportes | | 2:0 (1:0) |
| Medellín |
Copa Libertadores 1994, Group 1 |
| 05.04.1994 | | Olimpia | – | Independiente Medellín | | 0:2 (0:1) |
| Asunción |
Copa Libertadores 1994, Group 1 |
| 16.03.1994 | | Independiente Medellín | – | Cerro Porteño | | 3:0 (2:0) |
| Medellín |
Copa Libertadores 1994, Group 1 |
| 04.03.1994 | | Junior | – | Independiente Medellín | | 0:1 (0:1) |
| Barranquilla |
Copa Libertadores 1967, First Round, Group 2 |
| 10.05.1967 | | Independiente Medellín | – | 31 de Octubre | | 3:0 (2:0) |
| Medellín |
Copa Libertadores 1967, First Round, Group 2 |
| 07.05.1967 | | Independiente Medellín | – | Bolívar | | 2:0 (1:0) |
| Medellín |
Copa Libertadores 1967, First Round, Group 2 |
| 26.04.1967 | | 31 de Octubre | – | Independiente Medellín | | 1:2 (1:1) |
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