Copa Libertadores 2018, Group 4 |
 | 23.05.2018 | | Emelec | – | Santa Fe | | 0:3 (0:1) |
| Guayaquil |
Copa Libertadores 2018, Third qualifying stage |
| 20.02.2018 | | Santa Fe | – | Santiago Wanderers | | 3:0 (1:0) |
| Bogotá |
Copa Libertadores 2018, Third qualifying stage |
| 13.02.2018 | | Santiago Wanderers | – | Santa Fe | | 1:2 (0:2) |
| Valparaíso |
Copa Libertadores 2018, Second qualifying stage |
| 01.02.2018 | | Deportivo Táchira | – | Santa Fe | | 2:3 (2:2) |
| San Cristóbal |
Copa Libertadores 2017, Group 2 |
| 17.05.2017 | | Sporting Cristal | – | Santa Fe | | 0:2 (0:1) |
| Lima |
Copa Libertadores 2017, Group 2 |
| 16.03.2017 | | Santa Fe | – | Sporting Cristal | | 3:0 (1:0) |
| Bogotá |
Copa Libertadores 2016, Group 8 |
| 15.03.2016 | | Santa Fe | – | Cobresal | | 3:0 (2:0) |
| Bogotá |
Copa Libertadores 2016, Group 8 |
| 09.03.2016 | | Cobresal | – | Santa Fe | | 1:2 (0:2) |
| El Salvador |
Copa Libertadores 2016, Preliminary Round |
| 11.02.2016 | | Santa Fe | – | Oriente Petrolero | | 3:0 (2:0) |
| Bogotá |
Copa Libertadores 2016, Preliminary Round |
| 04.02.2016 | | Oriente Petrolero | – | Santa Fe | | 1:3 (0:2) |
| Santa Cruz de la Sierra |
Copa Libertadores 2015, Quarterfinal |
| 20.05.2015 | | Santa Fe | – | Internacional | | 1:0 (0:0) |
| Bogotá |
Copa Libertadores 2015, Round of 16 |
| 12.05.2015 | | Santa Fe | – | Estudiantes | | 2:0 (1:0) |
| Bogotá |
Copa Libertadores 2015, Group 1 |
| 22.04.2015 | | Santa Fe | – | Atlas | | 3:1 (2:0) |
| Bogotá |
Copa Libertadores 2015, Group 1 |
| 15.04.2015 | | Colo-Colo | – | Santa Fe | | 0:3 (0:1) |
| Santiago |
Copa Libertadores 2015, Group 1 |
| 26.02.2015 | | Santa Fe | – | Colo-Colo | | 3:1 (2:0) |
| Bogotá |
Copa Libertadores 2015, Group 1 |
| 17.02.2015 | | Atlas | – | Santa Fe | | 0:1 (0:0) |
| Guadalajara |
Copa Libertadores 2014, Group 4 |
| 11.02.2014 | | Santa Fe | – | Nacional Asunción | | 3:1 (0:0) |
| Bogotá |
Copa Libertadores 2014, Preliminary Round |
| 04.02.2014 | | Santa Fe | – | Monarcas | | 1:0 (0:0) |
| Bogotá |
Copa Libertadores 2013, Semifinal |
| 09.07.2013 | | Santa Fe | – | Olimpia | | 1:0 (0:0) |
| Bogotá |
Copa Libertadores 2013, Quarterfinal |
| 28.05.2013 | | Santa Fe | – | Real Garcilaso | | 2:0 (1:0) |
| Bogotá |
Copa Libertadores 2013, Quarterfinal |
| 22.05.2013 | | Real Garcilaso | – | Santa Fe | | 1:3 (0:2) |
| Cuzco |
Copa Libertadores 2013, Round of 16 |
| 16.05.2013 | | Santa Fe | – | Grêmio | | 1:0 (0:0) |
| Bogotá |
Copa Libertadores 2013, Group 6 |
| 16.04.2013 | | Santa Fe | – | Real Garcilaso | | 2:0 (0:0) |
| Bogotá |
Copa Libertadores 2013, Group 6 |
| 09.04.2013 | | Deportes Tolima | – | Santa Fe | | 1:2 (0:0) |
| Ibagué |
Copa Libertadores 2013, Group 6 |
| 02.04.2013 | | Santa Fe | – | Cerro Porteño | | 1:0 (1:0) |
| Bogotá |
Copa Libertadores 2013, Group 6 |
| 07.03.2013 | | Cerro Porteño | – | Santa Fe | | 1:2 (1:0) |
| Asunción |
Copa Libertadores 2006, 1/8 finals |
| 02.05.2006 | | Santa Fe | – | Guadalajara | | 3:1 (1:1) |
| Bogotá |
Copa Libertadores 2006, Group 2 |
| 13.04.2006 | | Santa Fe | – | Sporting Cristal | | 2:1 (2:0) |
| Bogotá |
Copa Libertadores 2006, Group 2 |
| 09.03.2006 | | Santa Fe | – | Estudiantes La Plata | | 3:1 (1:1) |
| Bogotá |
Copa Libertadores 2006, Group 2 |
| 09.02.2006 | | Sporting Cristal | – | Santa Fe | | 1:2 (1:0) |
| Lima |
Copa Libertadores 1980, First Round, Group 4 |
| 02.04.1980 | | Santa Fe | – | Universidad Católica | | 1:0 (0:0) |
| Bogotá |
Copa Libertadores 1980, First Round, Group 4 |
| 16.03.1980 | | Emelec | – | Santa Fe | | 0:2 (0:1) |
| Guayaquil |
Copa Libertadores 1976, First Round, Group 4 |
| 25.03.1976 | | Santa Fe | – | Los Millonarios | | 1:0 (0:0) |
| Bogotá |
Copa Libertadores 1972, First Round, Group 1 |
| 09.03.1972 | | Atlético Nacional | – | Santa Fe | | 0:1 (0:1) |
| Medellín |
Copa Libertadores 1967, First Round, Group 2 |
| 14.05.1967 | | Independiente Medellín | – | Santa Fe | | 0:4 (0:2) |
| Medellín |
Copa Libertadores 1967, First Round, Group 2 |
| 07.05.1967 | | Santa Fe | – | 31 de Octubre | | 2:0 (1:0) |
| |
Copa Libertadores 1967, First Round, Group 2 |
| 19.02.1967 | | Santa Fe | – | Independiente Medellín | | 2:0 (1:0) |
| Bogotá |
Copa Libertadores 1961, Quarterfinal |
| 07.05.1961 | | Santa Fe | – | Jorge Wilstermann | | 1:0 (1:0) |
| Bogotá |
Copa Libertadores 1961, First Round |
| 02.04.1961 | | Santa Fe | – | Barcelona | | 3:0 (0:0) |
| Bogotá |
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