FA Cup 2021/22, Extra Preliminary Round |
 | 07.08.2021 |  | Vauxhall Motors | – | Skelmersdale United | | 0:0 |
| Ellesmere Port |
FA Cup 2019/20, Extra Preliminary Round |
| 09.08.2019 | | Skelmersdale United | – | Penistone Church | | 1:1 (0:0) |
| Skelmersdale |
FA Cup 2016/17, First Qualifying Round |
| 03.09.2016 | | Dunston UTS | – | Skelmersdale United | | 2:2 |
| Dunston |
FA Cup 2015/16, First Qualifying Round |
| 12.09.2015 | | Glossop North End | – | Skelmersdale United | | 1:1 (0:0) |
| Glossop |
FA Cup 2005/06, Second Qualifying Round |
| 24.09.2005 | | Skelmersdale United | – | Bishop Auckland | | 0:0 |
| |
FA Cup 2004/05, Preliminary Round |
| | | Skelmersdale United | – | Stocksbridge Park Steels | | 1:1 |
| |
FA Cup 2000/01, Preliminary Round |
| | | Skelmersdale United | – | Guiseley | | 1:1 |
| |
FA Cup 1994/95, First Qualifying Round |
| | | Frickley Athletic | – | Skelmersdale United | | 1:1 |
| |
FA Cup 1990/91, Preliminary Round |
| | | Glossop | – | Skelmersdale United | | 1:1 |
| |
FA Cup 1989/90, Preliminary Round |
| | | Skelmersdale United | – | Curzon Ashton | | 1:1 |
| |
FA Cup 1988/89, First Qualifying Round |
| | | Morecambe | – | Skelmersdale United | | 3:3 |
| |
FA Cup 1985/86, First Qualifying Round |
| | | Skelmersdale United | – | Horwich Railway Mechanics Institute | | 2:2 |
| |
FA Cup 1980/81, Preliminary Round |
| | | Porthmadog | – | Skelmersdale United | | 1:1 |
| |
FA Cup 1978/79, First Qualifying Round |
| | | Hyde United | – | Skelmersdale United | | 1:1 |
| |
FA Cup 1976/77, Preliminary Round |
| | | New Brighton | – | Skelmersdale United | | 1:1 |
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FA Cup 1970/71, Fourth Qualifying Round |
| | | Skelmersdale United | – | Wigan Athletic | | 1:1 |
| |
FA Cup 1966/67, Second Qualifying Round |
| | | Lostock Gralam | – | Skelmersdale United | | 1:1 |
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FA Cup 1965/66, First Qualifying Round |
| | | Skelmersdale United | – | Leyland Motors | | 2:2 |
| |
FA Cup 1964/65, Second Qualifying Round |
| | | Skelmersdale United | – | South Liverpool | | 2:2 |
| |
FA Cup 1964/65, First Qualifying Round |
| | | Skelmersdale United | – | Droylsden | | 0:0 |
| |
FA Cup 1963/64, First Qualifying Round |
| | | Marine | – | Skelmersdale United | | 2:2 |
| |
FA Cup 1960/61, Third Qualifying Round |
| | | Skelmersdale United | – | Wigan Athletic | | 0:0 |
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FA Cup 1959/60, Preliminary Round |
| | | Skelmersdale United | – | Mossley | | 0:0 |
| |
FA Cup 1958/59, Third Qualifying Round |
| | | Skelmersdale United | – | Chorley | | 2:2 |
| |
FA Cup 1953/54, First Qualifying Round |
| | | Skelmersdale United | – | Chorley | | 1:1 |
| |
FA Cup 1951/52, Third Qualifying Round |
| | | Skelmersdale United | – | Darwen | | 1:1 |
| |
FA Cup 1951/52, Second Qualifying Round |
| | | Rossendale United | – | Skelmersdale United | | 1:1 |
| |
FA Cup 1947/48, Second Qualifying Round |
| | | Prescot Cables | – | Skelmersdale United | | 1:1 |
| |
FA Cup 1946/47, Third Qualifying Round |
| | | Skelmersdale United | – | Darwen | | 1:1 |
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FA Cup 1946/47, Second Qualifying Round |
| | | Chorley | – | Skelmersdale United | | 1:1 aet * |
| |
FA Cup 1946/47, Second Qualifying Round |
| | | Skelmersdale United | – | Chorley | | 1:1 |
| |
FA Cup 1945/46, Second Qualifying Round |
| | | Darwen | – | Skelmersdale United | | 2:2 |
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