CONCACAF Champions Cup 2024, Final tournament, Round of 16 |
 | 13.03.2024 |  | América | – | Guadalajara | | 2:3 (0:2) |
| Ciudad de México |
CONCACAF Champions Cup 2024, Final tournament, Round One |
| 13.02.2024 | | Guadalajara | – | Forge |  | 2:1 (1:0) |
| Guadalajara |
CONCACAF Champions Cup 2024, Final tournament, Round One |
| 07.02.2024 | | Forge | – | Guadalajara | | 1:3 (1:2) |
| Hamilton |
CONCACAF Champions League 2018, Final tournament, Final |
| 17.04.2018 | | Toronto | – | Guadalajara | | 1:2 (1:1) |
| Toronto |
CONCACAF Champions League 2018, Final tournament, Semifinal |
| 04.04.2018 | | Guadalajara | – | New York Red Bulls |  | 1:0 (1:0) |
| Guadalajara |
CONCACAF Champions League 2018, Final tournament, Quarterfinal |
| 14.03.2018 | | Guadalajara | – | Seattle Sounders | | 3:0 (0:0) |
| Guadalajara |
CONCACAF Champions League 2018, Final tournament, Round of 16 |
| 28.02.2018 | | Guadalajara | – | Cibao |  | 5:0 (1:0) |
| Guadalajara |
CONCACAF Champions League 2018, Final tournament, Round of 16 |
| 22.02.2018 | | Cibao | – | Guadalajara | | 0:2 (0:1) |
| Santiago de los Caballeros |
CONCACAF Champions League 2012/13, Final tournament, Group 8 |
| 25.10.2012 | | Guadalajara | – | Xelajú |  | 2:1 (1:0) |
| Guadalajara |
CONCACAF Champions League 2012/13, Final tournament, Group 8 |
| 29.08.2012 | | Guadalajara | – | Williams Connection |  | 4:0 (0:0) |
| Guadalajara |
CONCACAF Champions Cup 2006/07, Final tournament, Semifinal |
| 03.04.2007 | | Guadalajara | – | DC United | | 2:1 (1:1) |
| Guadalajara |
CONCACAF Champions Cup 2006/07, Final tournament, Quarterfinal |
| 28.02.2007 | | Guadalajara | – | Williams Connection | | 3:0 (1:0) |
| Guadalajara |
Copa de Campeones y Subcampeones CONCACAF 1997, Final tournament, Quarterfinal |
| 16.08.1997 | | Guadalajara | – | Cartaginés |  | 1:0 (1:0) |
| Guadalajara |
Copa de Campeones y Subcampeones CONCACAF 1984, Qualifying, Northern/Central Section, Round 3 |
| 31.10.1984 | | Guadalajara | – | Comunicaciones | | 4:1 (2:0) |
| Guadalajara |
Copa de Campeones y Subcampeones CONCACAF 1984, Qualifying, Northern/Central Section, Round 1 |
| 25.04.1984 | | Guadalajara | – | Águila |  | 3:0 (2:0) |
| Guadalajara |
Copa de Campeones y Subcampeones CONCACAF 1984, Qualifying, Northern/Central Section, Round 1 |
| 08.04.1984 | | Águila | – | Guadalajara | | 2:4 (1:0) |
| San Miguel |
Copa de Campeones y Subcampeones CONCACAF 1978, Qualifying, Northern Section, Round 2 |
| 16.08.1978 | | Guadalajara | – | Universidad Nacional | | 1:0 (1:0) |
| Guadalajara |
Copa de Campeones y Subcampeones CONCACAF 1978, Qualifying, Northern Section, Round 2 |
| 09.08.1978 | | Universidad Nacional | – | Guadalajara | | 0:1 (0:0) |
| Ciudad de México |
Copa de Campeones CONCACAF 1963, Semifinal |
| 18.08.1963 | | Guadalajara | – | Saprissa | | 2:0 (1:0) |
| Costa Rica, San José |
Copa de Campeones CONCACAF 1963, Semifinal |
| 14.08.1963 | | Saprissa | – | Guadalajara | | 0:1 (0:1) |
| San José |
Copa de Campeones CONCACAF 1963, Second Round |
| 13.06.1963 | | Guadalajara | – | New York Hungaria | | 2:0 |
| Guadalajara |
Copa de Campeones CONCACAF 1962, Final |
| 21.08.1962 | | Guadalajara | – | Comunicaciones | | 5:0 (2:0) |
| Guadalajara |
Copa de Campeones CONCACAF 1962, Final |
| 29.07.1962 | | Comunicaciones | – | Guadalajara | | 0:1 (0:1) |
| Ciudad de Guatemala |
Copa de Campeones CONCACAF 1962, First Round |
| 05.05.1962 | | Herediano | – | Guadalajara | | 0:3 (0:3) |
| Heredia |
Copa de Campeones CONCACAF 1962, First Round |
| 29.04.1962 | | Guadalajara | – | Herediano | | 2:0 (2:0) |
| Guadalajara |
Copa de Campeones y Subcampeones CONCACAF 1984, Qualifying, Northern/Central Section, Round 2 |
| | | Guadalajara | – | Jacksonville Tea Men | | +:- |
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