Copa Sudamericana 2023, First stage |
 | 08.03.2023 |  | Defensor Sporting | – | Danubio | | 0:0,
pen. 3:4 |
| Montevideo |
Copa Sudamericana 2018, Second round |
| 16.08.2018 | | Defensor Sporting | – | Fluminense |  | 0:1 (0:0) |
| Montevideo |
Copa Sudamericana 2018, Second round |
| 02.08.2018 | | Fluminense | – | Defensor Sporting | | 2:0 (0:0) |
| Rio de Janeiro |
Copa Sudamericana 2017, First Round |
| 30.05.2017 | | Defensor Sporting | – | LDU |  | 1:2 (0:1) |
| Montevideo |
Copa Sudamericana 2017, First Round |
| 28.02.2017 | | LDU | – | Defensor Sporting | | 2:2 (1:1) |
| Quito |
Copa Sudamericana 2015, Quarterfinal |
| 27.10.2015 | | Defensor Sporting | – | Huracán |  | 0:0 |
| Montevideo |
Copa Sudamericana 2015, Quarterfinal |
| 20.10.2015 | | Huracán | – | Defensor Sporting | | 1:0 (0:0) |
| Buenos Aires |
Copa Sudamericana 2015, Round of 16 |
| 01.10.2015 | | Defensor Sporting | – | Lanús | | 0:0,
pen. 5:3 |
| Montevideo |
Copa Sudamericana 2015, Round of 16 |
| 24.09.2015 | | Lanús | – | Defensor Sporting | | 0:0 |
| Lanús |
Copa Sudamericana 2015, Second round |
| 15.09.2015 |  | Universitario de Deportes | – | Defensor Sporting | | 0:1 (0:1) |
| Lima |
Copa Sudamericana 2015, Second round |
| 26.08.2015 | | Defensor Sporting | – | Universitario de Deportes | | 3:0 (0:0) |
| Montevideo |
Copa Sudamericana 2015, First Round |
| 18.08.2015 |  | Bolívar | – | Defensor Sporting | | 2:0 (0:0) |
| La Paz |
Copa Sudamericana 2015, First Round |
| 12.08.2015 | | Defensor Sporting | – | Bolívar | | 3:0 (1:0) |
| Montevideo |
Copa Sudamericana 2010, Round of 16 |
| 19.10.2010 | | Independiente | – | Defensor Sporting | | 4:2 (3:1) |
| Avellaneda |
Copa Sudamericana 2010, Round of 16 |
| 28.09.2010 | | Defensor Sporting | – | Independiente | | 1:0 (0:0) |
| Montevideo |
Copa Sudamericana 2010, First Round |
| 22.09.2010 | | Sport Huancayo | – | Defensor Sporting | | 2:0 (1:0) |
| Huancayo |
Copa Sudamericana 2010, First Round |
| 16.09.2010 | | Defensor Sporting | – | Sport Huancayo | | 9:0 (2:0) |
| Montevideo |
Copa Sudamericana 2010, Preliminary Round |
| 02.09.2010 |  | Olimpia | – | Defensor Sporting | | 1:1 (0:0) |
| Asunción |
Copa Sudamericana 2010, Preliminary Round |
| 03.08.2010 | | Defensor Sporting | – | Olimpia | | 2:0 (1:0) |
| Montevideo |
Copa Sudamericana 2008, Round of 16 |
| 02.10.2008 | | River Plate | – | Defensor Sporting | | 2:1 (1:0) |
| Buenos Aires |
Copa Sudamericana 2008, Round of 16 |
| 25.09.2008 | | Defensor Sporting | – | River Plate | | 1:2 (0:1) |
| Montevideo |
Copa Sudamericana 2008, First Round |
| 26.08.2008 | | Libertad | – | Defensor Sporting | | 3:3 (1:2) |
| Asunción |
Copa Sudamericana 2008, First Round |
| 19.08.2008 | | Defensor Sporting | – | Libertad | | 2:1 (0:0) |
| Montevideo |
Copa Sudamericana 2007, Quarterfinal |
| 30.10.2007 | | River Plate | – | Defensor Sporting | | 0:0 |
| Buenos Aires |
Copa Sudamericana 2007, Quarterfinal |
| 25.10.2007 | | Defensor Sporting | – | River Plate | | 2:2 (1:2) |
| Montevideo |
Copa Sudamericana 2007, Round of 16 |
| 04.10.2007 | | El Nacional | – | Defensor Sporting | | 2:0 (2:0) |
| Quito |
Copa Sudamericana 2007, Round of 16 |
| 20.09.2007 | | Defensor Sporting | – | El Nacional | | 3:0 (1:0) |
| Montevideo |
Copa Sudamericana 2007, Section 6, Second Stage |
| 13.09.2007 | | Defensor Sporting | – | Tacuary | | 3:0 (1:0) |
| Montevideo |
Copa Sudamericana 2007, Section 6, Second Stage |
| 30.08.2007 | | Tacuary | – | Defensor Sporting | | 1:1 (1:0) |
| Asunción |
Copa Sudamericana 2007, Section 6, First Stage |
| 21.08.2007 | | Libertad | – | Defensor Sporting | | 2:2 (1:2) |
| Asunción |
Copa Sudamericana 2007, Section 6, First Stage |
| 07.08.2007 | | Defensor Sporting | – | Libertad | | 2:1 (1:1) |
| Montevideo |
Copa Sudamericana 2005, Section 5, Second Stage |
| 06.09.2005 | | Defensor Sporting | – | Cerro Porteño | | 1:1 (0:1) |
| Montevideo |
Copa Sudamericana 2005, Section 5, Second Stage |
| 30.08.2005 | | Cerro Porteño | – | Defensor Sporting | | 2:0 (1:0) |
| Ciudad del Este |
Copa Sudamericana 2005, Section 5, First Stage |
| 23.08.2005 | | Danubio | – | Defensor Sporting | | 1:3 (1:1) |
| Montevideo |
Copa Sudamericana 2005, Section 5, First Stage |
| 16.08.2005 | | Defensor Sporting | – | Danubio | | 2:3 (1:1) |
| Montevideo |
