Copa Sudamericana 2024, First stage |
 | 05.03.2024 |  | Universidad Católica | – | Coquimbo Unido | | 0:2 (0:0) |
| Concepción |
Copa Sudamericana 2023, First stage |
| 07.03.2023 | | Audax Italiano | – | Universidad Católica | | 3:2 (1:2) |
| Rancagua |
Copa Sudamericana 2022, Round of 16 |
| 07.07.2022 |  | São Paulo | – | Universidad Católica | | 4:1 (2:0) |
| São Paulo |
Copa Sudamericana 2022, Round of 16 |
| 30.06.2022 | | Universidad Católica | – | São Paulo | | 2:4 (0:3) |
| Santiago |
Copa Sudamericana 2020, Quarterfinal |
| 15.12.2020 | | Universidad Católica | – | Vélez Sársfield |  | 1:3 (0:1) * |
| Santiago |
Copa Sudamericana 2020, Round of 16 |
| 03.12.2020 | | Universidad Católica | – | River Plate Montevideo |  | 0:1 (0:0) * |
| Santiago |
Copa Sudamericana 2020, First stage |
| 12.02.2020 | | Lanús | – | Universidad Católica | | 3:0 (0:0) |
| Lanús |
Copa Sudamericana 2019, Second round |
| 23.05.2019 |  | Independiente del Valle | – | Universidad Católica | | 5:0 (4:0) |
| Quito |
Copa Sudamericana 2016, First Round |
| 09.08.2016 |  | Real Potosí | – | Universidad Católica Santiago | | 3:1 (1:0) |
| Potosí |
Copa Sudamericana 2015, Second round |
| 17.09.2015 |  | Libertad | – | Universidad Católica Santiago | | 1:0 (1:0) |
| Asunción |
Copa Sudamericana 2015, Second round |
| 27.08.2015 | | Universidad Católica Santiago | – | Libertad | | 2:3 (2:0) |
| Santiago |
Copa Sudamericana 2014, First Round |
| 27.08.2014 | | River Plate Montevideo | – | Universidad Católica Santiago | | 3:0 (0:0) |
| Montevideo |
Copa Sudamericana 2014, First Round |
| 21.08.2014 | | Universidad Católica Santiago | – | River Plate Montevideo | | 0:1 (0:0) |
| Santiago |
Copa Sudamericana 2013, Round of 16 |
| 23.10.2013 | | Universidad Católica | – | São Paulo | | 3:4 (2:2) |
| Santiago |
Copa Sudamericana 2012, Round of 16 |
| 24.10.2012 | | Atlético | – | Universidad Católica | | 3:1 (2:1) |
| Goiânia |
Copa Sudamericana 2012, Second round |
| 18.09.2012 |  | Deportes Tolima | – | Universidad Católica | | 3:1 (2:0) |
| Ibagué |
Copa Sudamericana 2011, Round of 16 |
| 05.10.2011 | | Universidad Católica | – | Vélez Sársfield | | 0:2 (0:2) |
| Santiago |
Copa Sudamericana 2008, Preliminary Round |
| 29.07.2008 | | River Plate | – | Universidad Católica | | 2:0 (1:0) |
| Montevideo |
Copa Sudamericana 2005, Semifinal |
| 01.12.2005 | | Universidad Católica | – | Boca Juniors | | 0:1 (0:0) |
| Santiago |
Copa Sudamericana 2005, Quarterfinal |
| 18.10.2005 | | Fluminense | – | Universidad Católica | | 2:1 (2:0) |
| Rio de Janeiro |
Copa Sudamericana 2005, Section 3, Second Stage |
| 07.09.2005 |  | Alianza Atlético | – | Universidad Católica | | 2:0 (1:0) |
| San Miguel de Piura |
Copa Sudamericana 2005, Section 3, First Stage |
| 25.08.2005 | | Universidad Católica | – | Universidad de Chile | | 0:1 (0:0) |
| Santiago |
Copa Sudamericana 2003, Section 4, Second Stage |
| 25.09.2003 | | Cienciano | – | Universidad Católica | | 4:0 (2:0) |
| Cuzco |
Copa Sudamericana 2003, Section 4, First Stage |
| 05.08.2003 | | Universidad Católica | – | Provincial Osorno | | 0:1 (0:1) |
| Santiago |
