CAF Champions League 2020/21, Preliminary Round |
 | 29.11.2020 |  | FC Nouadhibou | – | Asante Kotoko |  | 1:1 (1:1) |
| Nouadhibou Stade Municipal |
CAF Champions League 2015, Round of 32 |
| 14.03.2015 |  | El Eulma | – | Asante Kotoko | | 0:0 |
| El Eulma |
CAF Champions League 2013, Round of 32 |
| 07.04.2013 | | Asante Kotoko | – | JSM Bejaia | | 1:1 (1:0) |
| Kumasi |
CAF Champions League 2013, Round of 32 |
| 15.03.2013 | | JSM Bejaia | – | Asante Kotoko | | 0:0 |
| Béjaïa |
CAF Champions League 2006, Group A |
| 13.08.2006 | | Asante Kotoko | – | Al Ahly Cairo |  | 0:0 |
| Obuasi |
CAF Champions League 2006, 1/16 Finals |
| 19.03.2006 |  | Ferroviário | – | Asante Kotoko | | 0:0 |
| |
CAF Champions League 2006, Preliminary Round |
| 19.02.2006 |  | Aigle Royal de la Menoua | – | Asante Kotoko | | 1:1 (0:1) |
| |
CAF Champions League 2004, 1/16 Finals |
| 25.04.2004 | | Asante Kotoko | – | ASEC |  | 0:0 |
| |
CAF Champions League 2004, 1/16 Finals |
| 11.04.2004 | | ASEC | – | Asante Kotoko | | 1:1 (0:0) |
| |
African Cup of Champions Clubs 1993, Final |
| 10.12.1993 | | Zamalek | – | Asante Kotoko | | 0:0 aet,
pen. 7:6 |
| Cairo |
African Cup of Champions Clubs 1993, Final |
| 26.11.1993 | | Asante Kotoko | – | Zamalek | | 0:0 |
| Kumasi |
African Cup of Champions Clubs 1983, Final |
| 27.11.1983 | | Al Ahly Cairo | – | Asante Kotoko | | 0:0 |
| Cairo |
African Cup of Champions Clubs 1982, Final |
| 12.12.1982 | | Asante Kotoko | – | Al Ahly Cairo | | 1:1 (1:0) |
| Kumasi |
African Cup of Champions Clubs 1970/71, Final |
| 10.01.1971 | | Asante Kotoko | – | TP Englebert |  | 1:1 (1:0) |
| Kumasi |
African Cup of Champions Clubs 1967, Final |
| 26.11.1967 | | TP Englebert | – | Asante Kotoko | | 2:2 aet |
| Kinshasa |
African Cup of Champions Clubs 1967, Final |
| 19.11.1967 | | Asante Kotoko | – | TP Englebert | | 1:1 |
| Kumasi |
African Cup of Champions Clubs 1993, First Round |
| |  | Sahel | – | Asante Kotoko | | 0:0 |
| |
African Cup of Champions Clubs 1992, First Round |
| | | Mikishi | – | Asante Kotoko | | 1:1 |
| |
African Cup of Champions Clubs 1990, First Round |
| |  | Freetown United | – | Asante Kotoko | | 1:1 |
| |
African Cup of Champions Clubs 1990, Second Round |
| |  | FAR | – | Asante Kotoko | | 3:3 |
| |
African Cup of Champions Clubs 1990, Quarterfinal |
| |  | Al Hilal | – | Asante Kotoko | | 2:2 |
| |
African Cup of Champions Clubs 1987, Second Round |
| | | WAC Casablanca | – | Asante Kotoko | | 1:1 |
| |
African Cup of Champions Clubs 1984, First Round |
| | | Asante Kotoko | – | Primeiro de Maio |  | 1:1 |
| |
African Cup of Champions Clubs 1982, Second Round |
| |  | Invincible Eleven | – | Asante Kotoko | | 0:0 |
| |
African Cup of Champions Clubs 1982, Quarterfinal |
| |  | Kampala City Council | – | Asante Kotoko | | 1:1 |
| |
African Cup of Champions Clubs 1981, First Round |
| | | Invincible Eleven | – | Asante Kotoko | | 1:1 |
| |
African Cup of Champions Clubs 1973, Second Round |
| | | Al Merreikh | – | Asante Kotoko | | 1:1 |
| |
African Cup of Champions Clubs 1971, Quarterfinal |
| | | Ismaily | – | Asante Kotoko | | 0:0 |
| |
African Cup of Champions Clubs 1971, Semifinal |
| | | Great Olympics | – | Asante Kotoko | | 1:1 |
| |
African Cup of Champions Clubs 1970/71, Quarterfinal |
| |  | Young Africans | – | Asante Kotoko | | 1:1 |
| |
African Cup of Champions Clubs 1970/71, Semifinal |
| | | Ismaily | – | Asante Kotoko | | 0:0 |
| |
African Cup of Champions Clubs 1969/70, First Round |
| |  | Patronage Sainte Anne | – | Asante Kotoko | | 1:1 |
| |
African Cup of Champions Clubs 1969/70, Quarterfinal |
| | | Asante Kotoko | – | Young Africans | | 1:1 |
| |
African Cup of Champions Clubs 1969/70, Quarterfinal |
| | | Young Africans | – | Asante Kotoko | | 1:1 |
| |
African Cup of Champions Clubs 1969/70, Semifinal |
| | | Asante Kotoko | – | Ismaily | | 2:2 |
| |
African Cup of Champions Clubs 1967, Semifinal |
| | | Asante Kotoko | – | Djoliba |  | 1:1 |
| |
African Cup of Champions Clubs 1966, Quarterfinal |
| | | Stade | – | Asante Kotoko | | 2:2 |
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