Copa Libertadores 2022, Group E |
 | 19.05.2022 |  | Deportivo Cali | – | Always Ready |  | 3:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 2022, Group E |
| 05.04.2022 | | Deportivo Cali | – | Boca Juniors |  | 2:0 (0:0) |
| Santiago de Cali |
Copa Libertadores 2014, Group 3 |
| 13.03.2014 | | Deportivo Cali | – | Lanús | | 2:1 (0:1) |
| Santiago de Cali |
Copa Libertadores 2014, Group 3 |
| 12.02.2014 | | Deportivo Cali | – | Cerro Porteño |  | 1:0 (0:0) |
| Santiago de Cali |
Copa Libertadores 2004, 1/8 finals |
| 05.05.2004 | | Deportivo Cali | – | Cruzeiro |  | 1:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 2004, Group 8 |
| 21.04.2004 | | Deportivo Cali | – | Colo-Colo |  | 3:1 (1:0) |
| Santiago de Cali |
Copa Libertadores 2004, Group 8 |
| 02.03.2004 | | Deportivo Cali | – | Bolívar | | 3:1 (1:0) |
| Santiago de Cali |
Copa Libertadores 2004, Group 8 |
| 03.02.2004 | | Colo-Colo | – | Deportivo Cali | | 2:3 (1:2) |
| Santiago |
Copa Libertadores 2003, Group 1 |
| 01.04.2003 | | Deportivo Cali | – | Emelec |  | 1:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 2003, Group 1 |
| 11.03.2003 | | Deportivo Cali | – | Libertad | | 1:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 2003, Group 1 |
| 25.02.2003 | | Emelec | – | Deportivo Cali | | 0:4 (0:1) |
| Guayaquil |
Copa Libertadores 2003, Group 1 |
| 19.02.2003 | | Deportivo Cali | – | River Plate | | 2:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 2001, Group 8 |
| 02.05.2001 | | Deportivo Cali | – | Boca Juniors | | 3:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 2001, Group 8 |
| 20.04.2001 | | Deportivo Cali | – | Oriente Petrolero | | 4:1 (3:0) |
| Santiago de Cali |
Copa Libertadores 2001, Group 8 |
| 02.03.2001 | | Oriente Petrolero | – | Deportivo Cali | | 1:3 (1:2) |
| Santa Cruz de la Sierra |
Copa Libertadores 1999, Final |
| 02.06.1999 | | Deportivo Cali | – | Palmeiras | | 1:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1999, Semifinal |
| 19.05.1999 | | Deportivo Cali | – | Cerro Porteño | | 4:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1999, Quarterfinal |
| 05.05.1999 | | Deportivo Cali | – | Bella Vista |  | 2:1 (1:1) |
| Santiago de Cali |
Copa Libertadores 1999, 1/8 finals |
| 14.04.1999 | | Deportivo Cali | – | Colo-Colo | | 2:0 (2:0) |
| Santiago de Cali |
Copa Libertadores 1999, Group 2 |
| 11.03.1999 | | Deportivo Cali | – | Vélez Sársfield | | 1:0 (0:0) |
| Santiago de Cali |
Copa Libertadores 1999, Group 2 |
| 04.03.1999 | | Deportivo Cali | – | River Plate | | 1:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1999, Group 2 |
| 24.02.1999 | | Deportivo Cali | – | Once Caldas | | 1:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1997, Group 5 |
| 11.03.1997 | | Deportivo Cali | – | Peñarol | | 2:0 (0:0) |
| Santiago de Cali |
Copa Libertadores 1987, First Round, Group 2 |
| 09.06.1987 | | Deportivo Cali | – | The Strongest | | 4:0 (2:0) |
| Santiago de Cali |
Copa Libertadores 1987, First Round, Group 2 |
| 02.06.1987 | | Deportivo Cali | – | Oriente Petrolero | | 5:1 (3:0) |
| Santiago de Cali |
Copa Libertadores 1987, First Round, Group 2 |
| 26.05.1987 | | Deportivo Cali | – | América de Cali | | 2:1 (2:0) |
| Santiago de Cali |
Copa Libertadores 1987, First Round, Group 2 |
| 15.05.1987 | | Oriente Petrolero | – | Deportivo Cali | | 0:1 (0:0) |
| Santa Cruz de la Sierra |
Copa Libertadores 1986, First Round, Group 2 |
| 15.04.1986 | | Universidad Católica | – | Deportivo Cali | | 1:3 (1:2) |
| Santiago |
Copa Libertadores 1986, First Round, Group 2 |
| 04.04.1986 | | Deportivo Cali | – | Universidad Católica | | 3:1 (1:0) |
| Santiago de Cali |
Copa Libertadores 1981, Semifinal group 1 |
| 16.10.1981 | | Deportivo Cali | – | Jorge Wilstermann | | 1:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1981, First Round, Group 1 |
| 22.04.1981 | | River Plate | – | Deportivo Cali | | 1:2 (1:1) |
| Buenos Aires |
Copa Libertadores 1981, First Round, Group 1 |
| 09.04.1981 | | Deportivo Cali | – | Junior | | 4:1 (2:1) |
| Santiago de Cali |
Copa Libertadores 1981, First Round, Group 1 |
| 03.04.1981 | | Deportivo Cali | – | River Plate | | 2:1 (1:0) |
| Santiago de Cali |
Copa Libertadores 1981, First Round, Group 1 |
| 31.03.1981 | | Deportivo Cali | – | Rosario Central | | 1:0 (0:0) |
| Santiago de Cali |
Copa Libertadores 1979, First Round, Group 1 |
| 04.04.1979 | | Deportivo Cali | – | Los Millonarios | | 2:0 (0:0) |
| Santiago de Cali |
Copa Libertadores 1979, First Round, Group 1 |
| 23.03.1979 | | Deportivo Cali | – | Independiente Avellaneda | | 1:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1979, First Round, Group 1 |
| 20.03.1979 | | Deportivo Cali | – | Quilmes | | 3:2 (1:1) |
| Santiago de Cali |
Copa Libertadores 1978, Semifinal group 2 |
| 18.10.1978 | | Cerro Porteño | – | Deportivo Cali | | 0:4 (0:1) |
| Asunción |
Copa Libertadores 1978, Semifinal group 2 |
| 14.10.1978 |  | Alianza Lima | – | Deportivo Cali | | 1:4 (0:1) |
| Lima |
Copa Libertadores 1978, Semifinal group 2 |
| 21.09.1978 | | Deportivo Cali | – | Alianza Lima | | 3:2 (2:2) |
| Santiago de Cali |
Copa Libertadores 1978, First Round, Group 4 |
| 18.07.1978 | | Peñarol | – | Deportivo Cali | | 0:2 (0:1) |
| Montevideo |
Copa Libertadores 1978, First Round, Group 4 |
| 17.05.1978 | | Deportivo Cali | – | Danubio | | 2:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1978, First Round, Group 4 |
| 14.05.1978 | | Deportivo Cali | – | Peñarol | | 1:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1977, First Round, Group 2 |
| 22.05.1977 | | Deportivo Cali | – | Oriente Petrolero | | 3:0 (2:0) |
| Santiago de Cali |
Copa Libertadores 1977, First Round, Group 2 |
| 19.05.1977 | | Deportivo Cali | – | Bolívar | | 3:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1977, First Round, Group 2 |
| 15.05.1977 | | Deportivo Cali | – | Atlético Nacional | | 3:1 (1:1) |
| Santiago de Cali |
Copa Libertadores 1977, First Round, Group 2 |
| 27.04.1977 | | Atlético Nacional | – | Deportivo Cali | | 0:3 (0:2) |
| Medellín |
Copa Libertadores 1975, First Round, Group 3 |
| 13.03.1975 | | Deportivo Cali | – | Vasco da Gama | | 2:1 (1:1) |
| Santiago de Cali |
Copa Libertadores 1975, First Round, Group 3 |
| 09.03.1975 | | Deportivo Cali | – | Cruzeiro | | 1:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1971, First Round, Group 5 |
| 28.03.1971 | | Deportivo Cali | – | Junior | | 2:0 (1:0) |
| Santiago de Cali |
Copa Libertadores 1971, First Round, Group 5 |
| 21.03.1971 | | Deportivo Cali | – | Barcelona | | 3:1 (0:0) |
| Santiago de Cali |
Copa Libertadores 1971, First Round, Group 5 |
| 18.03.1971 | | Deportivo Cali | – | Emelec | | 1:0 (0:0) |
| Santiago de Cali |
Copa Libertadores 1970, First Round, Group 3 |
| 18.03.1970 | | Rangers | – | Deportivo Cali | | 0:2 (0:0) |
| Talca |
Copa Libertadores 1970, First Round, Group 3 |
| 11.03.1970 | | América de Cali | – | Deportivo Cali | | 2:4 (1:3) |
| Santiago de Cali |
Copa Libertadores 1970, First Round, Group 3 |
| 01.03.1970 | | Deportivo Cali | – | América de Cali | | 4:2 (3:1) |
| Santiago de Cali |
Copa Libertadores 1970, First Round, Group 3 |
| 25.02.1970 | | Deportivo Cali | – | Rangers | | 3:2 (0:1) |
| Santiago de Cali |
Copa Libertadores 1970, First Round, Group 3 |
| 15.02.1970 | | Deportivo Cali | – | Universidad de Chile | | 2:0 |
| Santiago de Cali |
Copa Libertadores 1969, Second round, group 2 |
| 06.04.1969 | | Deportivo Cali | – | Santiago Wanderers | | 5:1 (3:1) |
| Santiago de Cali |
Copa Libertadores 1969, First Round, Group 1 |
| 16.03.1969 | | Deportivo Cali | – | Canarias |  | 2:0 (0:0) |
| Santiago de Cali |
Copa Libertadores 1969, First Round, Group 1 |
| 13.03.1969 | | Deportivo Cali | – | Deportivo Italia | | 3:0 (2:0) |
| Santiago de Cali |
Copa Libertadores 1969, First Round, Group 1 |
| 09.03.1969 | | Deportivo Cali | – | Unión Magdalena | | 3:1 (1:1) |
| Santiago de Cali |
Copa Libertadores 1968, First Round, Group 1 |
| 28.02.1968 | | Deportivo Cali | – | Los Millonarios | | 1:0 (0:0) |
| Santiago de Cali |
Copa Libertadores 1968, First Round, Group 1 |
| 08.02.1968 | | Deportivo Cali | – | Independiente Avellaneda | | 1:0 (0:0) |
| Santiago de Cali |
