Europa League 2020/21, Play-off Round |
 | 01.10.2020 |  | Slovan Liberec | – | APOEL |  | 1:0 (0:0) * |
| Liberec |
Europa League 2019/20, Round of 32 |
| 27.02.2020 |  | Basel | – | APOEL | | 1:0 (1:0) |
| Basel |
Europa League 2019/20, Round of 32 |
| 20.02.2020 | | APOEL | – | Basel | | 0:3 (0:1) |
| Nicosia |
Europa League 2019/20, Group A |
| 03.10.2019 |  | Sevilla | – | APOEL | | 1:0 (1:0) |
| Sevilla |
Europa League 2019/20, Group A |
| 19.09.2019 | | APOEL | – | F91 |  | 3:4 (0:1) |
| Nicosia |
Europa League 2018/19, Play-off Round |
| 30.08.2018 |  | Astana | – | APOEL | | 1:0 aet
(1:0, 1:0),
pen. 2:1 |
| Astana |
Europa League 2018/19, Second qualifying round |
| 02.08.2018 |  | Flora | – | APOEL | | 2:0 (2:0) |
| Tallinn |
Europa League 2016/17, Round of 16 |
| 16.03.2017 |  | Anderlecht | – | APOEL | | 1:0 (0:0) |
| Bruxelles |
Europa League 2016/17, Round of 16 |
| 09.03.2017 | | APOEL | – | Anderlecht | | 0:1 (0:1) |
| Nicosia |
Europa League 2016/17, Round of 32 |
| 16.02.2017 | | Athletic | – | APOEL | | 3:2 (1:1) |
| Bilbao |
Europa League 2016/17, Group B |
| 24.11.2016 | | Astana | – | APOEL | | 2:1 (0:1) |
| Astana |
Europa League 2016/17, Group B |
| 20.10.2016 | | Young Boys | – | APOEL | | 3:1 (1:1) |
| Bern |
Europa League 2015/16, Group K |
| 10.12.2015 | | APOEL | – | Sparta Prague | | 1:3 (1:0) |
| Nicosia |
Europa League 2015/16, Group K |
| 26.11.2015 |  | Schalke 04 | – | APOEL | | 1:0 (0:0) |
| Gelsenkirchen |
Europa League 2015/16, Group K |
| 05.11.2015 |  | Asteras | – | APOEL | | 2:0 (2:0) |
| Tripoli |
Europa League 2015/16, Group K |
| 01.10.2015 | | Sparta Prague | – | APOEL | | 2:0 (1:0) |
| Praha |
Europa League 2015/16, Group K |
| 17.09.2015 | | APOEL | – | Schalke 04 | | 0:3 (0:2) |
| Nicosia |
Europa League 2013/14, Group F |
| 12.12.2013 | | Eintracht Frankfurt | – | APOEL | | 2:0 (0:0) |
 | Frankfurt am Main |
Europa League 2013/14, Group F |
| 24.10.2013 |  | Bordeaux | – | APOEL | | 2:1 (1:1) |
| Bordeaux |
Europa League 2013/14, Group F |
| 03.10.2013 | | APOEL | – | Eintracht Frankfurt | | 0:3 (0:1) |
| Nicosia |
Europa League 2013/14, Play-off Round |
| 29.08.2013 | | APOEL | – | Zulte Waregem | | 1:2 (0:1) |
| Nicosia |
Europa League 2012/13, Play-off Round |
| 30.08.2012 | | APOEL | – | Neftçi |  | 1:3 (1:2) |
| Nicosia |
Europa League 2010/11, Play-off Round |
| 19.08.2010 | | Getafe | – | APOEL | | 1:0 (1:0) |
| Getafe |
UEFA Cup 2008/09, First Round |
| 16.09.2008 | | APOEL | – | Schalke 04 | | 1:4 (0:3) |
| Nicosia |
UEFA Cup 2006/07, Second qualifying round |
| 24.08.2006 |  | Trabzonspor | – | APOEL | | 1:0 (0:0) |
| Trabzon |
UEFA Cup 2005/06, First Round |
| 29.09.2005 | | Hertha | – | APOEL | | 3:1 (2:0) |
| Berlin |
UEFA Cup 2005/06, First Round |
| 15.09.2005 | | APOEL | – | Hertha | | 0:1 (0:0) |
| Nicosia |
UEFA Cup 2003/04, 1/64 finals |
| 15.10.2003 | | Mallorca | – | APOEL | | 4:2 (1:1) |
| Palma de Mallorca |
UEFA Cup 2003/04, 1/64 finals |
| 24.09.2003 | | APOEL | – | Mallorca | | 1:2 (0:1) |
| Nicosia |
UEFA Cup 2002/03, 1/32 finals |
| 07.11.2002 | | Hertha | – | APOEL | | 4:0 (2:0) |
| Berlin |
UEFA Cup 2002/03, 1/32 finals |
| 31.10.2002 | | APOEL | – | Hertha | | 0:1 (0:0) |
| Nicosia |
UEFA Cup 2000/01, 1/64 finals |
| 28.09.2000 | | APOEL | – | Brugge | | 0:1 (0:1) |
| Nicosia |
UEFA Cup 2000/01, 1/64 finals |
| 14.09.2000 | | Brugge | – | APOEL | | 2:0 (1:0) |
| Brugge |
UEFA Cup 1999/00, Qualifying round |
| 26.08.1999 |  | Levski | – | APOEL | | 2:0 (0:0) |
| Sofia |
UEFA Cup 1996/97, 1/32 finals |
| 24.09.1996 | | Español | – | APOEL | | 1:0 (0:0) |
| Barcelona |
UEFA Cup 1988/89, 1/32 finals |
| 05.10.1988 | | APOEL | – | Velež |  | 2:5 (1:1) |
| Nicosia |
UEFA Cup 1988/89, 1/32 finals |
| 07.09.1988 | | Velež | – | APOEL | | 1:0 (1:0) |
| Mostar Gradski Stadion |
UEFA Cup 1985/86, 1/32 finals |
| 02.10.1985 | | Lokomotiv Sofia | – | APOEL | | 4:2 aet
(1:2, 2:2) |
| Sofia |
UEFA Cup 1981/82, 1/32 finals |
| 30.09.1981 |  | Argeş | – | APOEL | | 4:0 (2:0) |
| Piteşti |
UEFA Cup 1977/78, 1/32 finals |
| 14.09.1977 |  | Torino | – | APOEL | | 3:0 (2:0) |
| Torino |
