UEFA Champions League 2019/20, Third qualifying round |
 | 13.08.2019 |  | Qarabağ | – | APOEL |  | 0:2 (0:1) |
| Bakı |
UEFA Champions League 2019/20, Second qualifying round |
| 30.07.2019 | | APOEL | – | Sutjeska |  | 3:0 (2:0) |
| Nicosia |
UEFA Champions League 2019/20, Second qualifying round |
| 23.07.2019 | | Sutjeska | – | APOEL | | 0:1 (0:1) |
| Nikšić |
UEFA Champions League 2018/19, First Qualifying Round |
| 17.07.2018 | | APOEL | – | Sūduva |  | 1:0 (1:0) |
| Nicosia |
UEFA Champions League 2017/18, Play-off Round |
| 15.08.2017 | | APOEL | – | Slavia Praha |  | 2:0 (2:0) |
| Nicosia |
UEFA Champions League 2017/18, Third qualifying round |
| 02.08.2017 | | APOEL | – | Viitorul |  | 4:0 aet
(0:0, 1:0) |
| Nicosia |
UEFA Champions League 2017/18, Second qualifying round |
| 19.07.2017 |  | F91 | – | APOEL | | 0:1 (0:1) |
| Diddeleng |
UEFA Champions League 2017/18, Second qualifying round |
| 12.07.2017 | | APOEL | – | F91 | | 1:0 (0:0) |
| Nicosia |
UEFA Champions League 2016/17, Third qualifying round |
| 02.08.2016 | | APOEL | – | Rosenborg |  | 3:0 (0:0) |
| Nicosia |
UEFA Champions League 2016/17, Second qualifying round |
| 19.07.2016 | | APOEL | – | The New Saints |  | 3:0 (0:0) |
| Nicosia |
UEFA Champions League 2015/16, Third qualifying round |
| 28.07.2015 |  | Midtjylland | – | APOEL | | 1:2 (0:2) |
| Herning |
UEFA Champions League 2014/15, Play-off Round |
| 26.08.2014 | | APOEL | – | AaB | | 4:0 (2:0) |
 | Nicosia |
UEFA Champions League 2014/15, Third qualifying round |
| 06.08.2014 | | APOEL | – | HJK |  | 2:0 (2:0) |
| Nicosia |
UEFA Champions League 2011/12, Round of 16 |
| 07.03.2012 | | APOEL | – | Lyon |  | 1:0 aet
(1:0, 1:0),
pen. 4:3 |
| Nicosia |
UEFA Champions League 2011/12, Group G |
| 01.11.2011 | | APOEL | – | Porto |  | 2:1 (1:0) |
| Nicosia |
UEFA Champions League 2011/12, Group G |
| 13.09.2011 | | APOEL | – | Zenit |  | 2:1 (0:0) |
| Nicosia |
UEFA Champions League 2011/12, Play-off Round |
| 23.08.2011 | | APOEL | – | Wisła Kraków |  | 3:1 (1:0) |
| Nicosia |
UEFA Champions League 2011/12, Third qualifying round |
| 03.08.2011 |  | Slovan Bratislava | – | APOEL | | 0:2 (0:0) |
| Bratislava |
UEFA Champions League 2011/12, Second qualifying round |
| 20.07.2011 | | APOEL | – | Skënderbeu |  | 4:0 (0:0) |
| Nicosia |
UEFA Champions League 2011/12, Second qualifying round |
| 13.07.2011 | | Skënderbeu | – | APOEL | | 0:2 (0:0) |
| Korçë |
UEFA Champions League 2009/10, First Round |
| 26.08.2009 | | APOEL | – | København | | 3:1 (3:1) |
| Nicosia |
UEFA Champions League 2009/10, Third qualifying round |
| 29.07.2009 | | APOEL | – | Partizan |  | 2:0 (0:0) |
| Nicosia |
UEFA Champions League 2009/10, Second qualifying round |
| 21.07.2009 | | APOEL | – | Streymur |  | 3:0 (1:0) |
| Nicosia |
UEFA Champions League 2009/10, Second qualifying round |
| 14.07.2009 | | Streymur | – | APOEL | | 0:2 (0:1) |
| Tórshavn |
UEFA Champions League 2007/08, First Qualifying Round |
| 17.07.2007 | | APOEL | – | BATE |  | 2:0 (1:0) |
| Nicosia |
UEFA Champions League 2002/03, Second qualifying round |
| 07.08.2002 | | APOEL | – | Maribor |  | 4:2 (2:1) |
| Nicosia |
UEFA Champions League 2002/03, First Qualifying Round |
| 24.07.2002 | | APOEL | – | Flora |  | 1:0 (0:0) |
| Nicosia |
UEFA European Champions' Cup 1986/87, 1/16 finals |
| 17.09.1986 | | APOEL | – | HJK | | 1:0 (1:0) |
| Nicosia |
UEFA European Champions' Cup 1980/81, 1/16 finals |
| 01.10.1980 | | APOEL | – | Dynamo Berlin |  | 2:1 (1:0) |
| Nicosia |
